Anti-Thioredoxin Polyclonal Antibody
應用 IHC
稀釋比例IHC 1:25-100.
交叉反應Human

產(chǎn)品型號：K106714P

更新時間：2022-08-15

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Anti-Thioredoxin Polyclonal Antibody

英文名稱	Anti-Thioredoxin Polyclonal Antibody
宿主	Rabbit
別名	TRDX;TRX;TRX1;TXN
應用	IHC
稀釋比例	IHC 1:25-100.
交叉反應	Human
蛋白分子量	12kDa
Gene ID	7295
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human Thioredoxin
性狀	液體
Public Immunogen Range	A synthetic peptide of human Thioredoxin
Subcellular Locations	Nucleus Cytoplasm Secreted
Swiss Prot	P10599
克隆類型	Polyclonal Antibody
背景資料	Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.