Anti-NR3C2 Polyclonal Antibody
應用 WB
稀釋比例WB 1:500-2000.
交叉反應Human Mouse

產(chǎn)品型號：K106612P

更新時間：2022-08-15

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Anti-NR3C2 Polyclonal Antibody

英文名稱	Anti-NR3C2 Polyclonal Antibody
宿主	Rabbit
別名	MCR;MLR;MR;NR3C2VIT
應用	WB
稀釋比例	WB 1:500-2000.
交叉反應	Human Mouse
蛋白分子量	107kDa
Gene ID	4306
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human NR3C2
性狀	液體
Public Immunogen Range	A synthetic peptide of human NR3C2
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	P08235
克隆類型	Polyclonal Antibody
背景資料	This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.