Anti-XBP1 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號：K106477P

更新時間：2022-08-15

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Anti-XBP1 Polyclonal Antibody

英文名稱	Anti-XBP1 Polyclonal Antibody
宿主	Rabbit
別名	TREB-5;XBP2;TREB5;XBP-1;
應(yīng)用	WB
稀釋比例	WB 1:3000.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	45kDa
Gene ID	7494
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human XBP1
性狀	液體
Public Immunogen Range	A synthetic peptide of human XBP1
Subcellular Locations	Nucleus
Swiss Prot	P17861
克隆類型	Polyclonal Antibody
背景資料	This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1).